Aim of study: To find out if there is any differences or structural damage in the brain and spinal cord between cavaliers with and without clinical signs of pain associated with syringomyelia.
Sincere thanks to all the breeder and pet owner participation in Ontario Canada who worked with the investigators as part of the team. Another example of breeder/research co-operation which helps understanding of CMSM and help dogs.
24 age- matched Cavalier King Charles Spaniels were recruited and performed MRI for diagnostic or screening prior to breeding purposes. Owners completed a lifestyle questionnaire DTI was included in the MRI protocol requiring a combination of dedicated and experienced radiographers (Jane Sykes and Karen Kennedy) and a suitably powerful 3 Tesla MRI unit located in London Ontario
The DTI was interpreted by Dr Federico DiGuglielmo of the Clinical Neurological Sciences Department University Hospital, London, Ontario
Investigators : Dr Federico DiGuglielmo ,K Kennedy, J Sykes, John Butler, Frank Bihari, Lela Deans and C Rusbridge,
MRI Funding : For the Love of Ollie, Rupert’s Fund and Lawson Imaging
This study is nearing completion but still requires additional funds to finalise the investigation.